HitPredict

Interactor 1: UBP8 (P40818)
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)
Gene: USP8

Interactor 2: CHMP7 (Q8WUX9)
Charged multivesicular body protein 7 (Chromatin-modifying protein 7)
Gene: CHMP7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17711858
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030496 - midbody
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1118 Hs			1 453
+	Hs
		777084 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHMP5_HUMAN (225-431): 2.42e-42: 151: 19.44
+	Hs
		777063 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHM4C_HUMAN (223-432): 4.61e-42: 150: 23.94
+	Hs
		777078 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHM4B_HUMAN (222-431): 1.13e-41: 149: 20.09
+	Hs
		777065 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHMP6_HUMAN (227-425): 3.8e-38: 139: 25.13
+	Hs
		208820 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHM2A_HUMAN (221-401): 4.56e-37: 137: 12.30
+	Hs
		777087 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHM2B_HUMAN (229-428): 1.91e-37: 137: 13.59
+	Sc
		693626 UBP4_YEAST (535-1109): 1.21e-109: 366: 23.86		SNF7_YEAST (224-432): 5.68e-38: 139: 19.30
+	Sc
		693632 UBP4_YEAST (535-1109): 1.21e-109: 366: 23.86		VPS20_YEAST (226-432): 9.78e-35: 130: 15.57
+	Hs
		1024429 UBP4_HUMAN (964-1106): 5.42e-33: 140: 44.06		CHMP5_HUMAN (225-431): 2.42e-42: 151: 19.44
+	Hs
		1316089 UBP15_HUMAN (964-1106): 1.96e-34: 145: 49.65		CHM4A_HUMAN (222-429): 7.03e-40: 144: 20.00
+	Hs
		208873 UBP15_HUMAN (964-1106): 1.96e-34: 145: 49.65		CHM2A_HUMAN (221-401): 4.56e-37: 137: 12.30