HitPredict

Interactor 1: UBP8 (P40818)
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)
Gene: USP8

Interactor 2: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19302785
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000281 - mitotic cytokinesis GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030496 - midbody and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1118 Hs			1 224
+	Hs
		777063 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		777060 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHMP7_HUMAN (8-215): 5.6e-42: 149: 21.91
+	Hs
		777084 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHMP5_HUMAN (4-219): 7.09e-42: 143: 24.32
+	Hs
		777065 UBP8_HUMAN (1-1118): 0: 830: 100.00		CHMP6_HUMAN (4-204): 2.71e-28: 107: 20.30
+	Sc
		693626 UBP4_YEAST (535-1109): 1.21e-109: 366: 23.86		SNF7_YEAST (3-216): 1.69e-34: 124: 38.25
+	Sc
		693632 UBP4_YEAST (535-1109): 1.21e-109: 366: 23.86		VPS20_YEAST (11-221): 2.51e-32: 118: 20.91
+	Hs
		1316089 UBP15_HUMAN (964-1106): 1.96e-34: 145: 49.65		CHM4A_HUMAN (1-220): 2.41e-43: 147: 56.95
+	Hs
		1024429 UBP4_HUMAN (964-1106): 5.42e-33: 140: 44.06		CHMP5_HUMAN (4-219): 7.09e-42: 143: 24.32