HitPredict

Interactor 1: RFC5 (P40937)
Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36)
Gene: RFC5

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 768
+	Hs
		721984 RFC4_HUMAN (1-331): 9.47e-89: 272: 36.77		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		722105 RFC2_HUMAN (2-331): 2.97e-86: 265: 35.35		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		777982 RFC3_HUMAN (21-340): 6.47e-62: 202: 24.00		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		260139 VPS4B_HUMAN (2-315): 1e-55: 189: 11.18		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		722104 RFC2_HUMAN (2-331): 2.97e-86: 265: 35.35		CUL1_HUMAN (18-768): 0: 707: 30.57