Interactor 1: ECHA (P40939)
Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (Monolysocardiolipin acyltransferase) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]
Gene: HADHA

Interactor 2: AUHM (Q13825)
Methylglutaconyl-CoA hydratase, mitochondrial (3-MG-CoA hydratase) (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase) (Itaconyl-CoA hydratase) (EC 4.2.1.56)
Gene: AUH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 32877691
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 3HCDH~ECH_1, 3HCDH_N~ECH_1, ECH_1~ECH_1
Common GO terms GO:0004300 - enoyl-CoA hydratase activity
GO:0005739 - mitochondrion
GO:0006635 - fatty acid beta-oxidation
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 763
Hs

1 339
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ec
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024