Interactor 1: MAD1 (P40957)
Spindle assembly checkpoint component MAD1 (Mitotic arrest deficient protein 1)
Gene: MAD1

Interactor 2: MAD2 (P40958)
Mitotic spindle checkpoint component MAD2 (Mitotic MAD2 protein)
Gene: MAD2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 10436016, 12473689, 10837255, 16554755, 16818718, 37968396, 16429126
Identification Methods molecular sieving, coimmunoprecipitation, affinity chromatography technology, two hybrid, pull down, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HORMA~MAD
Common GO terms GO:0000776 - kinetochore
GO:0007094 - mitotic spindle assembly checkpoint signaling
GO:0044774 - mitotic DNA integrity checkpoint signaling
GO:0044877 - protein-containing complex binding
GO:0051301 - cell division
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 749
Sc

1 196
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024