HitPredict

Interactor 1: MAD1 (P40957)
Spindle assembly checkpoint component MAD1 (Mitotic arrest deficient protein 1)
Gene: MAD1

Interactor 2: CDC14 (Q00684)
Tyrosine-protein phosphatase CDC14 (EC 3.1.3.48)
Gene: CDC14

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	21127052
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0051301 - cell division GO:0072686 - mitotic spindle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 749 Sc			1 551
+	Hs
		148975 CTRO_HUMAN (52-672): 1.84e-62: 230: 13.91		SSH2_HUMAN (152-530): 4.75e-38: 151: 14.00
+	Mm
		139397 MRCKA_MOUSE (72-641): 6.1e-30: 129: 14.90		PTEN_MOUSE (152-540): 4.63e-74: 242: 14.53
+	Hs
		725123 MYH10_HUMAN (2-543): 3.38e-18: 92: 13.21		PTEN_HUMAN (152-540): 3.27e-74: 243: 14.53
+	Hs
		551649 DESP_HUMAN (49-652): 5.39e-12: 72: 10.57		PTEN_HUMAN (152-540): 3.27e-74: 243: 14.53
+	Mm
		139340 CTRO_MOUSE (61-543): 1.63e-09: 63.9: 12.27		PTEN_MOUSE (152-540): 4.63e-74: 242: 14.53
+	Hs
		254510 ROCK2_HUMAN (53-467): 5.65e-10: 65.1: 13.73		DUS16_HUMAN (192-546): 2.49e-65: 226: 15.39
+	Hs
		725210 MYH10_HUMAN (2-543): 3.38e-18: 92: 13.21		SSH1_HUMAN (212-450): 7.58e-41: 160: 10.93
+	Hs
		253766 MYH13_HUMAN (16-668): 3.45e-18: 92: 10.29		AUXI_HUMAN (145-389): 9.52e-40: 156: 14.73
+	Hs
		724891 MYH9_HUMAN (319-728): 7.51e-15: 81.2: 7.81		SSH2_HUMAN (152-530): 4.75e-38: 151: 14.00
+	Hs
		260524 MYH9_HUMAN (319-728): 7.51e-15: 81.2: 7.81		TP4A3_HUMAN (188-362): 3.27e-40: 145: 23.20
+	Hs
		551686 DESP_HUMAN (49-652): 5.39e-12: 72: 10.57		DUS4_HUMAN (189-397): 9.77e-38: 145: 16.51
+	Hs
		260572 MYH14_HUMAN (24-660): 7.39e-12: 71.5: 9.53		TP4A3_HUMAN (188-362): 3.27e-40: 145: 23.20