HitPredict

Interactor 1: PRS7 (P35998)
26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2)
Gene: PSMC2

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 433 Hs			1 156
+	Hs
		975372 PRS10_HUMAN (39-429): 1.7e-121: 360: 42.46		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Hs
		968871 PRS8_HUMAN (37-430): 1.42e-120: 358: 45.43		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Mm
		509158 Q8BVQ9_MOUSE (1-433): 1.62e-145: 424: 99.77		UBC_MOUSE (1-119): 1.08e-36: 135: 67.48
+	Rn
		1224390 PRS7_RAT (1-433): 4.21e-145: 422: 99.77		UBC_RAT (1-119): 1.58e-36: 134: 68.29
+	Hs
		968680 PRS4_HUMAN (1-428): 1.12e-134: 396: 40.23		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	At
		1168320 PRS7A_ARATH (10-433): 7.23e-141: 411: 80.43		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Mm
		509013 PRS4_MOUSE (1-428): 1.12e-134: 396: 40.23		UBC_MOUSE (1-119): 1.08e-36: 135: 67.48
+	Hs
		975373 PRS10_HUMAN (39-429): 1.7e-121: 360: 42.46		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Hs
		968872 PRS8_HUMAN (37-430): 1.42e-120: 358: 45.43		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Mm
		509016 PRS10_MOUSE (39-429): 1.7e-121: 360: 42.46		UBC_MOUSE (1-119): 1.08e-36: 135: 67.48
+	Rn
		108148 G3V6W6_RAT (39-429): 2.69e-121: 360: 42.46		UBC_RAT (1-119): 1.58e-36: 134: 68.29
+	At
		1167904 PRS8A_ARATH (5-430): 9.38e-124: 367: 44.50		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Mm
		509014 PRS8_MOUSE (37-430): 1.42e-120: 358: 45.43		UBC_MOUSE (1-119): 1.08e-36: 135: 67.48
+	At
		1168199 PS10B_ARATH (24-430): 9.22e-123: 364: 40.79		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		1167868 PRS8B_ARATH (33-430): 2.34e-122: 363: 45.87		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		1168248 PS6AA_ARATH (7-431): 2.85e-117: 351: 38.35		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		1168249 PS10A_ARATH (34-429): 8.79e-117: 348: 41.46		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		1168161 CD48E_ARATH (161-408): 1.41e-82: 272: 39.52		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		1168236 CD48D_ARATH (161-433): 7.55e-83: 272: 37.00		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81