HitPredict

Interactor 1: SCD2 (P40996)
Protein scd2/ral3
Gene: SCD2

Interactor 2: PPK2 (Q10447)
Protein kinase domain-containing protein ppk2
Gene: PPK2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23615447
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051286 - cell tip
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 536 Sp			1 665
+	Sp
		778941 SCD2_SCHPO (1-536): 3.22e-167: 486: 100.00		STE20_SCHPO (43-655): 6.91e-126: 389: 19.17
+	Sc
		666281 BEM1_YEAST (2-492): 2.43e-81: 265: 29.28		STE20_YEAST (184-652): 1.19e-117: 375: 20.37
+	Hs
		277595 NCK1_HUMAN (3-271): 7.74e-36: 139: 14.80		PAK3_HUMAN (132-661): 5.19e-128: 391: 16.37
+	Hs
		209044 NCK2_HUMAN (4-271): 1.15e-35: 139: 13.41		PAK1_HUMAN (134-658): 1.31e-125: 384: 16.20
+	Hs
		557676 NCK1_HUMAN (3-271): 7.74e-36: 139: 14.80		PAK1_HUMAN (134-658): 1.31e-125: 384: 16.20
+	Mm
		292046 NCK1_MOUSE (3-271): 1.26e-35: 138: 14.80		PAK1_MOUSE (146-649): 4.73e-122: 375: 16.48
+	Hs
		209045 NCK2_HUMAN (4-271): 1.15e-35: 139: 13.41		PAK2_HUMAN (268-661): 3.75e-120: 369: 16.54
+	Hs
		557677 NCK1_HUMAN (3-271): 7.74e-36: 139: 14.80		PAK2_HUMAN (268-661): 3.75e-120: 369: 16.54
+	Hs
		1026922 SPD2A_HUMAN (299-470): 1.12e-28: 123: 21.93		PAK2_HUMAN (268-661): 3.75e-120: 369: 16.54
+	Hs
		537638 NCF1_HUMAN (2-296): 8.15e-25: 108: 12.50		PAK1_HUMAN (134-658): 1.31e-125: 384: 16.20
+	Dm
		1214366 NCK_DROME (31-297): 1.05e-27: 118: 16.84		PAK_DROME (281-657): 3.13e-119: 373: 18.59
+	Hs
		580979 PLCG1_HUMAN (29-174): 1.06e-17: 89: 15.82		KPCE_HUMAN (304-661): 1.06e-127: 396: 16.40
+	Hs
		277606 ITSN1_HUMAN (94-470): 3.73e-16: 84.4: 8.87		PAK3_HUMAN (132-661): 5.19e-128: 391: 16.37
+	Hs
		580997 PLCG1_HUMAN (29-174): 1.06e-17: 89: 15.82		PAK1_HUMAN (134-658): 1.31e-125: 384: 16.20
+	Hs
		235479 VINEX_HUMAN (23-182): 4.77e-15: 80.3: 23.75		AKT2_HUMAN (344-656): 4.72e-129: 391: 15.12
+	Hs
		235471 VINEX_HUMAN (23-182): 4.77e-15: 80.3: 23.75		KAPCA_HUMAN (349-658): 3.41e-127: 381: 16.15
+	Hs
		235500 VINEX_HUMAN (23-182): 4.77e-15: 80.3: 23.75		PAK2_HUMAN (268-661): 3.75e-120: 369: 16.54
+	Mm
		1113249 SRBS2_MOUSE (31-181): 2.83e-11: 68.3: 20.89		TAOK2_MOUSE (375-661): 1.6e-115: 376: 23.31
+	Hs
		235609 VINEX_HUMAN (23-182): 4.77e-15: 80.3: 23.75		PAK5_HUMAN (355-636): 6.67e-115: 362: 21.68
+	Sc
		666298 BEM1_YEAST (2-492): 2.43e-81: 265: 29.28		SKM1_YEAST (412-637): 1.41e-11: 69.7: 24.79