HitPredict

Interactor 1: CCNF (P41002)
Cyclin-F (F-box only protein 1)
Gene: CCNF

Interactor 2: CDC6 (Q99741)
Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)
Gene: CDC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	26818844, 33961781, 36114006
Identification Methods	affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051301 - cell division
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 786 Hs			1 560
+	Hs
		722073 CCNF_HUMAN (1-786): 0: 952: 100.00		RFC2_HUMAN (139-512): 1.14e-64: 216: 14.66
+	Hs
		777823 CCNF_HUMAN (1-786): 0: 952: 100.00		RFC5_HUMAN (162-518): 3.37e-64: 215: 17.04
+	Hs
		538599 CCNB1_HUMAN (130-537): 8.12e-120: 369: 19.00		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		590219 CCNA2_HUMAN (141-536): 3.28e-99: 315: 22.28		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		624607 CCNE1_HUMAN (177-567): 1.06e-93: 300: 16.14		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		943785 CCNA1_HUMAN (191-537): 1.27e-109: 344: 25.49		ORC1_HUMAN (4-548): 3.74e-94: 308: 22.62
+	Xl
		936141 Q66J45_XENLA (155-537): 6.09e-110: 343: 22.45		P70049_XENLA (2-548): 1.74e-90: 298: 23.70
+	Hs
		590177 CCNA2_HUMAN (141-536): 3.28e-99: 315: 22.28		ORC1_HUMAN (4-548): 3.74e-94: 308: 22.62
+	Sp
		737066 CG22_SCHPO (157-557): 3.46e-101: 320: 19.08		CDC18_SCHPO (9-552): 5.47e-83: 271: 25.47
+	Sp
		500275 CG23_SCHPO (113-527): 4.08e-98: 314: 19.08		CDC18_SCHPO (9-552): 5.47e-83: 271: 25.47