Interactor 1: IF2G (P41091)
Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF2-gamma X) (eIF2gX)
Gene: EIF2S3
Interactor 2: IF5 (P55010)
Eukaryotic translation initiation factor 5 (eIF-5)
Gene: EIF5
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35271311 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | GTP_EFTU~eIF-5_eIF-2B, GTP_EFTU_D2~eIF-5_eIF-2B |
| Common GO terms | GO:0001731 - formation of translation preinitiation complex GO:0003743 - translation initiation factor activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Sc |   |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Hv | |
|
|||||||||||
| + | Hv | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
