HitPredict

Interactor 1: OPRD (P41143)
Delta-type opioid receptor (D-OR-1) (DOR-1)
Gene: OPRD1

Interactor 2: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	11259507
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	7tm_1~Arrestin_C, 7tm_1~Arrestin_N
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 418
+	Hs
		827128 CCR5_HUMAN (35-365): 2.36e-81: 254: 23.44		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		441649 ADRB1_HUMAN (1-354): 2.29e-74: 240: 18.78		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		674834 AGTR1_HUMAN (38-369): 3.77e-72: 230: 28.74		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Rn
		626613 AGTRA_RAT (38-369): 1.51e-72: 231: 28.45		ARRB1_RAT (1-418): 0: 707: 99.04
+	Mm
		669680 AGTRA_MOUSE (38-371): 3.9e-72: 230: 28.28		ARRB1_MOUSE (1-418): 0: 703: 98.57
+	Hs
		685822 OPRD_HUMAN (1-372): 3.55e-101: 305: 100.00		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		428933 ADRB2_HUMAN (29-339): 2.14e-77: 245: 22.12		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		441648 ADRB1_HUMAN (1-354): 2.29e-74: 240: 18.78		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Rn
		663954 Q8VBU7_RAT (45-363): 7.93e-77: 244: 21.90		ARRB2_RAT (1-407): 0: 616: 75.00
+	Hs
		685813 APJ_HUMAN (51-367): 3.24e-72: 231: 27.88		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		674827 AGTR1_HUMAN (38-369): 3.77e-72: 230: 28.74		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Rn
		626614 AGTRA_RAT (38-369): 1.51e-72: 231: 28.45		ARRB2_RAT (1-407): 0: 616: 75.00