HitPredict

Interactor 1: B5B2U4 (B5B2U4)
Nuclear factor of activated T-cells c3 isoform IB-Xa
Gene: Nfatc3

Interactor 2: TNFA (P06804)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: Tnf

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	16260608
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1068 Mm			1 235
+	Hs
		352598 NFAC3_HUMAN (1-1035): 1.12e-156: 494: 89.96		TNFA_HUMAN (1-235): 2.1e-104: 303: 78.39
+	Hs
		155683 NFAC3_HUMAN (1-1035): 1.12e-156: 494: 89.96		TNF11_HUMAN (49-235): 5.29e-58: 188: 20.10
+	Mm
		420392 NFKB1_MOUSE (421-939): 1.02e-107: 361: 15.68		TNFA_MOUSE (1-235): 4.5e-105: 305: 100.00
+	Hs
		352606 NFAC2_HUMAN (41-1003): 4.46e-80: 283: 32.68		TNFA_HUMAN (1-235): 2.1e-104: 303: 78.39
+	Hs
		317883 NFAC1_HUMAN (19-880): 4.08e-77: 275: 38.67		TNFA_HUMAN (1-235): 2.1e-104: 303: 78.39
+	Hs
		352617 NFAC4_HUMAN (1-864): 6.07e-71: 256: 39.80		TNFA_HUMAN (1-235): 2.1e-104: 303: 78.39
+	Mm
		420398 RELB_MOUSE (382-848): 6.71e-62: 223: 15.86		TNFA_MOUSE (1-235): 4.5e-105: 305: 100.00
+	Hs
		352584 RELB_HUMAN (327-848): 9.84e-58: 211: 15.67		TNFA_HUMAN (1-235): 2.1e-104: 303: 78.39
+	Mm
		420397 TF65_MOUSE (418-904): 1.93e-48: 183: 19.11		TNFA_MOUSE (1-235): 4.5e-105: 305: 100.00
+	Hs
		352589 TF65_HUMAN (418-904): 8.87e-48: 182: 18.44		TNFA_HUMAN (1-235): 2.1e-104: 303: 78.39
+	Hs
		300514 NFAT5_HUMAN (319-936): 2.24e-45: 180: 27.14		TNFA_HUMAN (1-235): 2.1e-104: 303: 78.39
+	Mm
		420412 NFAT5_MOUSE (319-936): 1.7e-42: 171: 26.17		TNFA_MOUSE (1-235): 4.5e-105: 305: 100.00
+	Hs
		669879 REL_HUMAN (429-1038): 1.75e-105: 345: 18.59		CD40L_HUMAN (83-235): 6.82e-37: 131: 22.98
+	Hs
		669883 NFAC2_HUMAN (41-1003): 4.46e-80: 283: 32.68		CD40L_HUMAN (83-235): 6.82e-37: 131: 22.98
+	Hs
		317913 NFAC1_HUMAN (19-880): 4.08e-77: 275: 38.67		CD40L_HUMAN (83-235): 6.82e-37: 131: 22.98
+	Hs
		815717 MYO15_HUMAN (84-452): 3.76e-11: 69.9: 11.28		TNFL6_HUMAN (19-235): 1.21e-64: 203: 26.34