HitPredict

Interactor 1: BCL6 (P41182)
B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51)
Gene: BCL6

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	25416956, 27107012
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 706 Hs			1 197
+	Hs
		993497 ZNF34_HUMAN (499-691): 1.96e-74: 252: 32.58		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		993504 ZN383_HUMAN (311-496): 1.97e-09: 62.3: 11.11		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00