HitPredict

Interactor 1: BCL6 (P41182)
B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51)
Gene: BCL6

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.707

The method score is based on:

Property	Details
Experiments	9627120, 15454082, 9753732, 10611298, 16147992
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001222 - transcription corepressor binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 2 others more... GO:0045892 - negative regulation of DNA-templated transcription GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	706
Hs

1	482

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024