HitPredict

Interactor 1: BCL6 (P41182)
B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51)
Gene: BCL6

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.679

The method score is based on:

Property	Details
Experiments	9753732, 9765306, 16147992
Identification Methods	affinity chromatography technology, pull down, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 4 others more... GO:0008104 - protein localization GO:0031507 - heterochromatin formation GO:0045666 - positive regulation of neuron differentiation GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	706
Hs

1	1273

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024