HitPredict

Interactor 1: CETN2 (P41208)
Centrin-2 (Caltractin isoform 1)
Gene: CETN2

Interactor 2: EFC11 (Q9BUY7)
EF-hand calcium-binding domain-containing protein 11
Gene: EFCAB11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~EF-hand_7, EF-hand_7~EF-hand_8
Common GO terms	GO:0005509 - calcium ion binding GO:0008017 - microtubule binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 172 Hs			1 163
+	Hs
		1016740 CETN1_HUMAN (1-172): 2.41e-65: 199: 83.72		EFC11_HUMAN (1-163): 1.13e-68: 207: 100.00
+	Hs
		171165 CETN3_HUMAN (16-166): 1.28e-42: 141: 57.62		EFC11_HUMAN (1-163): 1.13e-68: 207: 100.00
+	At
		1104924 CDPK4_ARATH (1-170): 2.37e-51: 173: 30.41		CDPK4_ARATH (4-160): 5.93e-45: 155: 22.15
+	At
		1105900 CDPKB_ARATH (1-170): 1.94e-51: 173: 30.41		CDPKB_ARATH (4-160): 6.8e-45: 155: 22.15
+	Hs
		171125 CETN3_HUMAN (16-166): 1.28e-42: 141: 57.62		CETN2_HUMAN (4-156): 1.37e-47: 154: 24.68
+	Hs
		483908 CETN2_HUMAN (1-172): 1.7e-67: 204: 100.00		CALM1_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		483980 CETN2_HUMAN (1-172): 1.7e-67: 204: 100.00		CALM2_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		484069 CETN2_HUMAN (1-172): 1.7e-67: 204: 100.00		CALM3_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		781544 CETN2_HUMAN (1-172): 1.7e-67: 204: 100.00		CETN1_HUMAN (90-162): 2.14e-09: 55.4: 27.40
+	At
		989458 CDPK1_ARATH (1-171): 1.74e-52: 177: 25.58		CDPK1_ARATH (28-155): 1.82e-12: 66: 20.16
+	At
		188361 CDPKU_ARATH (1-172): 2.27e-50: 171: 26.01		CML8_ARATH (83-163): 3.94e-13: 64.8: 20.99
+	At
		483177 CDPKU_ARATH (1-172): 2.27e-50: 171: 26.01		CALM4_ARATH (3-86): 4.85e-11: 59.1: 21.18
+	At
		886638 CDPKU_ARATH (1-172): 2.27e-50: 171: 26.01		CALM7_ARATH (3-86): 5.44e-11: 59.1: 21.18
+	At
		976699 CDPKU_ARATH (1-172): 2.27e-50: 171: 26.01		CALM6_ARATH (3-86): 8.26e-11: 58.7: 22.35
+	Hs
		171115 CETN3_HUMAN (16-166): 1.28e-42: 141: 57.62		CALM1_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		171116 CETN3_HUMAN (16-166): 1.28e-42: 141: 57.62		CALM2_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		171117 CETN3_HUMAN (16-166): 1.28e-42: 141: 57.62		CALM3_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		171132 CETN3_HUMAN (16-166): 1.28e-42: 141: 57.62		CETN1_HUMAN (90-162): 2.14e-09: 55.4: 27.40
+	At
		886540 CALM6_ARATH (101-168): 3.42e-12: 62.5: 45.59		CALM7_ARATH (3-86): 5.44e-11: 59.1: 21.18