HitPredict

Interactor 1: ETV6 (P41212)
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)
Gene: ETV6

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	10377438, 25416956
Identification Methods	two hybrid, pull down, affinity chromatography technology, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 452 Hs			1 158
+	Hs
		541997 ETS1_HUMAN (5-443): 3.24e-108: 328: 21.83		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		849307 ELF3_HUMAN (16-422): 6.22e-92: 285: 19.66		UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12
+	Hs
		919706 ELF3_HUMAN (16-422): 6.22e-92: 285: 19.66		UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07
+	Hs
		840431 ETV1_HUMAN (118-450): 8.23e-85: 270: 23.30		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		781150 ETV5_HUMAN (93-450): 1.38e-61: 210: 17.47		UB2E3_HUMAN (3-156): 2.14e-68: 207: 33.77
+	Hs
		930147 FLI1_HUMAN (248-419): 4.21e-41: 154: 24.42		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		584229 ELK1_HUMAN (341-424): 9.37e-38: 144: 45.24		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Ce
		106129 G5EDL0_CAEEL (335-422): 4.72e-36: 139: 36.36		UBC9_CAEEL (1-157): 3.2e-68: 205: 76.43
+	Dm
		843570 PNT_DROME (18-156): 1.13e-15: 81.7: 24.11		Q7KNM2_DROME (1-158): 1.41e-66: 201: 85.44