HitPredict

Interactor 1: TRAF6 (B5DF45)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: TNR16 (P07174)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: Ngfr

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27494324
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0042475 - odontogenesis of dentin-containing tooth
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Rn			1 425
+	Hs
		436651 TRAF6_HUMAN (1-530): 1.02e-150: 443: 86.42		TNR16_HUMAN (4-425): 3.71e-111: 334: 92.24
+	Hs
		584509 TRAF6_HUMAN (1-530): 1.02e-150: 443: 86.42		TNR1A_HUMAN (19-419): 6.24e-74: 240: 19.04
+	Hs
		436618 TRAF2_HUMAN (38-508): 1.05e-106: 330: 27.15		TNR16_HUMAN (4-425): 3.71e-111: 334: 92.24
+	Mm
		648955 TRAF6_MOUSE (1-530): 3.87e-148: 437: 95.85		TNR5_MOUSE (10-256): 7.09e-52: 177: 22.63
+	Hs
		591438 TRAF6_HUMAN (1-530): 1.02e-150: 443: 86.42		TNR1B_HUMAN (6-302): 1.83e-46: 168: 19.02
+	Hs
		639668 TRAF6_HUMAN (1-530): 1.02e-150: 443: 86.42		TNR5_HUMAN (11-256): 3.87e-47: 164: 19.85
+	Mm
		192585 TRAF6_MOUSE (1-530): 3.87e-148: 437: 95.85		TNR11_MOUSE (9-213): 1.61e-42: 160: 22.17
+	Hs
		1377881 TRAF6_HUMAN (1-530): 1.02e-150: 443: 86.42		TNR11_HUMAN (28-211): 4.82e-38: 147: 24.47
+	Mm
		626852 TRAF2_MOUSE (38-508): 9.78e-108: 332: 27.55		TNR1A_MOUSE (19-423): 7.36e-74: 239: 19.32
+	Hs
		1334961 TRAF6_HUMAN (1-530): 1.02e-150: 443: 86.42		TNR27_HUMAN (33-137): 9.56e-17: 82.2: 19.49
+	Hs
		154352 TRAF2_HUMAN (38-508): 1.05e-106: 330: 27.15		TR10B_HUMAN (27-422): 1.32e-56: 194: 15.57
+	Mm
		936250 TRAF6_MOUSE (1-530): 3.87e-148: 437: 95.85		TNR27_MOUSE (33-137): 1.71e-17: 84.6: 18.64
+	Mm
		648951 TRAF2_MOUSE (38-508): 9.78e-108: 332: 27.55		TNR5_MOUSE (10-256): 7.09e-52: 177: 22.63
+	Mm
		192583 TRAF2_MOUSE (38-508): 9.78e-108: 332: 27.55		TNR11_MOUSE (9-213): 1.61e-42: 160: 22.17
+	Mm
		761824 TRAF2_MOUSE (38-508): 9.78e-108: 332: 27.55		TNR14_MOUSE (12-203): 1.04e-39: 145: 26.63
+	Mm
		761804 TRAF2_MOUSE (38-508): 9.78e-108: 332: 27.55		TNR4_MOUSE (32-248): 2.38e-35: 133: 23.87
+	Mm
		761805 TRAF2_MOUSE (38-508): 9.78e-108: 332: 27.55		TNR3_MOUSE (22-314): 2.48e-34: 133: 17.09
+	Mm
		591445 TRAF2_MOUSE (38-508): 9.78e-108: 332: 27.55		TNR9_MOUSE (42-221): 6.87e-32: 123: 21.98
+	Hs
		121479 TRAF2_HUMAN (38-508): 1.05e-106: 330: 27.15		TR10A_HUMAN (46-154): 5.46e-27: 114: 23.42
+	Mm
		761802 TRAF2_MOUSE (38-508): 9.78e-108: 332: 27.55		CD27_MOUSE (12-128): 1.36e-23: 100: 23.33