HitPredict

Interactor 1: B5DFF9 (B5DFF9)
Protein inhibitor of activated STAT, 4
Gene: Pias4

Interactor 2: SUMO1 (Q5I0H3)
Small ubiquitin-related modifier 1 (SUMO-1)
Gene: SUMO1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21454665
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rad60-SLD~zf-MIZ
Common GO terms	GO:0005634 - nucleus GO:0016925 - protein sumoylation GO:0031625 - ubiquitin protein ligase binding GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 507 Rn			1 101
+	Rn
		78200 B5DFF9_RAT (1-507): 0: 599: 100.00		SUMO3_RAT (1-100): 1.5e-39: 128: 46.00
+	Hs
		928135 PIAS4_HUMAN (1-507): 0: 583: 87.18		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00
+	Hs
		902668 PIAS4_HUMAN (1-507): 0: 583: 87.18		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		879136 PIAS4_HUMAN (1-507): 0: 583: 87.18		SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42
+	Hs
		928241 PIAS3_HUMAN (3-506): 2.81e-168: 491: 46.04		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00
+	Mm
		222291 PIAS3_MOUSE (3-506): 2.63e-166: 486: 45.84		SUMO1_MOUSE (1-101): 1.01e-41: 134: 100.00
+	Hs
		278040 PIAS1_HUMAN (3-505): 8.4e-166: 485: 44.34		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00
+	Hs
		102146 PIAS1_HUMAN (3-505): 8.4e-166: 485: 44.34		SUMO5_HUMAN (1-101): 4.52e-41: 132: 88.12
+	Hs
		902827 PIAS3_HUMAN (3-506): 2.81e-168: 491: 46.04		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		879167 PIAS3_HUMAN (3-506): 2.81e-168: 491: 46.04		SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42
+	Hs
		278020 PIAS1_HUMAN (3-505): 8.4e-166: 485: 44.34		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		278009 PIAS1_HUMAN (3-505): 8.4e-166: 485: 44.34		SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42
+	Hs
		278256 PIAS2_HUMAN (3-506): 5.25e-161: 472: 44.93		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00
+	Hs
		102147 PIAS2_HUMAN (3-506): 5.25e-161: 472: 44.93		SUMO5_HUMAN (1-101): 4.52e-41: 132: 88.12
+	Rn
		1140374 PIAS2_RAT (3-503): 6.41e-163: 475: 44.80		SUMO3_RAT (1-100): 1.5e-39: 128: 46.00
+	Hs
		278253 PIAS2_HUMAN (3-506): 5.25e-161: 472: 44.93		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		278250 PIAS2_HUMAN (3-506): 5.25e-161: 472: 44.93		SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42
+	At
		1147334 SIZ1_ARATH (3-483): 2.65e-132: 407: 20.29		SUMO2_ARATH (6-99): 5.11e-38: 124: 45.75
+	At
		1147333 SIZ1_ARATH (3-483): 2.65e-132: 407: 20.29		SUMO3_ARATH (6-97): 1.88e-37: 123: 38.04
+	At
		878961 SIZ1_ARATH (3-483): 2.65e-132: 407: 20.29		SUMO1_ARATH (9-95): 3e-35: 117: 47.13