HitPredict

Interactor 1: B5DFF9 (B5DFF9)
Protein inhibitor of activated STAT, 4
Gene: Pias4

Interactor 2: SUMO3 (Q5XIF4)
Small ubiquitin-related modifier 3 (SUMO-3)
Gene: SUMO3

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22082260
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rad60-SLD~zf-MIZ
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016925 - protein sumoylation GO:0019789 - SUMO transferase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 507 Rn			1 110
+	Rn
		78199 B5DFF9_RAT (1-507): 0: 599: 100.00		SUMO1_RAT (1-95): 2.48e-39: 128: 47.00
+	Hs
		879136 PIAS4_HUMAN (1-507): 0: 583: 87.18		SUMO3_HUMAN (1-92): 1.4e-43: 139: 100.00
+	Hs
		902668 PIAS4_HUMAN (1-507): 0: 583: 87.18		SUMO2_HUMAN (1-92): 4.84e-42: 135: 96.77
+	Hs
		928135 PIAS4_HUMAN (1-507): 0: 583: 87.18		SUMO1_HUMAN (1-95): 2.48e-39: 128: 47.00
+	Rn
		1140374 PIAS2_RAT (3-503): 6.41e-163: 475: 44.80		SUMO3_RAT (1-110): 3.29e-56: 171: 100.00
+	Hs
		879167 PIAS3_HUMAN (3-506): 2.81e-168: 491: 46.04		SUMO3_HUMAN (1-92): 1.4e-43: 139: 100.00
+	Hs
		902827 PIAS3_HUMAN (3-506): 2.81e-168: 491: 46.04		SUMO2_HUMAN (1-92): 4.84e-42: 135: 96.77
+	Hs
		278009 PIAS1_HUMAN (3-505): 8.4e-166: 485: 44.34		SUMO3_HUMAN (1-92): 1.4e-43: 139: 100.00
+	Hs
		278020 PIAS1_HUMAN (3-505): 8.4e-166: 485: 44.34		SUMO2_HUMAN (1-92): 4.84e-42: 135: 96.77
+	Hs
		928241 PIAS3_HUMAN (3-506): 2.81e-168: 491: 46.04		SUMO1_HUMAN (1-95): 2.48e-39: 128: 47.00
+	Mm
		222291 PIAS3_MOUSE (3-506): 2.63e-166: 486: 45.84		SUMO1_MOUSE (1-95): 2.48e-39: 128: 47.00
+	Hs
		278040 PIAS1_HUMAN (3-505): 8.4e-166: 485: 44.34		SUMO1_HUMAN (1-95): 2.48e-39: 128: 47.00
+	Hs
		278250 PIAS2_HUMAN (3-506): 5.25e-161: 472: 44.93		SUMO3_HUMAN (1-92): 1.4e-43: 139: 100.00
+	Hs
		102146 PIAS1_HUMAN (3-505): 8.4e-166: 485: 44.34		SUMO5_HUMAN (1-95): 4.1e-38: 125: 45.00
+	Hs
		278253 PIAS2_HUMAN (3-506): 5.25e-161: 472: 44.93		SUMO2_HUMAN (1-92): 4.84e-42: 135: 96.77
+	Hs
		278256 PIAS2_HUMAN (3-506): 5.25e-161: 472: 44.93		SUMO1_HUMAN (1-95): 2.48e-39: 128: 47.00
+	Hs
		102147 PIAS2_HUMAN (3-506): 5.25e-161: 472: 44.93		SUMO5_HUMAN (1-95): 4.1e-38: 125: 45.00
+	At
		1147334 SIZ1_ARATH (3-483): 2.65e-132: 407: 20.29		SUMO2_ARATH (1-97): 4.84e-42: 135: 48.45
+	At
		878961 SIZ1_ARATH (3-483): 2.65e-132: 407: 20.29		SUMO1_ARATH (2-98): 1.08e-37: 124: 46.39
+	At
		1147333 SIZ1_ARATH (3-483): 2.65e-132: 407: 20.29		SUMO3_ARATH (1-92): 4.28e-37: 123: 41.94