HitPredict

Interactor 1: RGS2 (P41220)
Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8)
Gene: RGS2

Interactor 2: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.620

Property	Details
Experiments	16169070, 21900206
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0010976 - positive regulation of neuron projection development
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 913
+	Hs
		180654 RGS16_HUMAN (31-198): 1.4e-57: 182: 47.70		SRC_HUMAN (361-912): 1.28e-125: 391: 23.60
+	Rn
		139846 RGS12_RAT (7-210): 2.6e-53: 185: 26.32		NTRK1_RAT (604-906): 3.59e-104: 343: 42.90
+	Hs
		384492 RGS19_HUMAN (13-210): 3.56e-63: 196: 29.80		NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27