HitPredict

Interactor 1: RGS2 (P41220)
Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8)
Gene: RGS2

Interactor 2: STXB4 (Q6ZWJ1)
Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip)
Gene: STXBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 553
+	Hs
		296590 RGS11_HUMAN (52-207): 7.93e-63: 203: 29.75		SNTA1_HUMAN (4-234): 6.27e-35: 139: 17.80
+	Rn
		250560 AXIN1_RAT (9-205): 1.52e-53: 184: 26.47		DVL1_RAT (2-277): 1.75e-31: 131: 16.13
+	Hs
		150651 AXIN1_HUMAN (9-205): 3.02e-53: 184: 26.47		DVL1_HUMAN (2-192): 2.77e-31: 130: 14.67
+	Hs
		150775 AXIN1_HUMAN (9-205): 3.02e-53: 184: 26.47		DVL2_HUMAN (2-192): 2.86e-30: 127: 16.90
+	Mm
		193183 AXIN1_MOUSE (9-205): 2.18e-52: 181: 26.47		DVL2_MOUSE (2-192): 4.19e-30: 127: 16.90
+	Hs
		782029 RGS2_HUMAN (1-211): 4.66e-76: 229: 100.00		PTN13_HUMAN (3-185): 4.49e-13: 74.5: 18.75
+	Mm
		956667 RGS14_MOUSE (80-197): 7.46e-17: 80.1: 35.83		DLG2_MOUSE (17-104): 1.85e-23: 106: 28.26
+	Mm
		956651 RGS14_MOUSE (80-197): 7.46e-17: 80.1: 35.83		LIN7A_MOUSE (12-101): 4.07e-22: 97.1: 35.56