HitPredict

Interactor 1: BUD31 (P41223)
Protein BUD31 homolog (Protein EDG-2) (Protein G10 homolog)
Gene: BUD31

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	G10~WD40
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0071007 - U2-type catalytic step 2 spliceosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 144 Hs			1 504
+	Sp
		144090 CWF14_SCHPO (1-143): 1.68e-78: 230: 59.72		PRP19_SCHPO (3-501): 3.8e-95: 298: 27.24
+	Hs
		782138 BUD31_HUMAN (1-144): 5.69e-89: 256: 100.00		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Sc
		629362 BUD31_YEAST (1-143): 1.72e-71: 212: 50.65		PRP19_YEAST (3-138): 1.03e-22: 103: 38.19