Interactor 1: KDM5C (P41229)
Lysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C)
Gene: KDM5C

Interactor 2: REST (Q13127)
RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor)
Gene: REST

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 0.60 0.565

The method score is based on:

Property Details
Experiments 17468742
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006338 - chromatin remodeling
GO:0006355 - regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1560
Hs

1 1097
+ Hs

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Last updated: 15 Jul 2024