HitPredict

Interactor 1: HNF4A (P41235)
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)
Gene: HNF4A

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 197
+	Hs
		782522 HNF4A_HUMAN (1-474): 0: 542: 100.00		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		369456 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		914640 ERR3_HUMAN (16-375): 8.56e-110: 334: 27.39		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		369457 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50