HitPredict

Interactor 1: HNF4A (P41235)
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)
Gene: HNF4A

Interactor 2: DPF1 (Q92782)
Zinc finger protein neuro-d4 (BRG1-associated factor 45B) (BAF45B) (D4, zinc and double PHD fingers family 1)
Gene: DPF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 474 Hs			1 387
+	Hs
		782608 HNF4A_HUMAN (1-474): 0: 542: 100.00		REQU_HUMAN (1-384): 3.36e-88: 273: 57.86
+	Hs
		782534 HNF4A_HUMAN (1-474): 0: 542: 100.00		CHD3_HUMAN (63-374): 3.32e-52: 189: 15.71
+	Hs
		782694 HNF4A_HUMAN (1-474): 0: 542: 100.00		KMT2B_HUMAN (126-384): 1.95e-36: 143: 18.75
+	Hs
		782600 HNF4A_HUMAN (1-474): 0: 542: 100.00		PHF10_HUMAN (214-374): 5.77e-33: 130: 34.15
+	Hs
		152605 HNF4A_HUMAN (1-474): 0: 542: 100.00		KMT2D_HUMAN (197-380): 3.16e-27: 116: 24.73
+	Hs
		370135 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		REQU_HUMAN (1-384): 3.36e-88: 273: 57.86
+	Hs
		782637 HNF4A_HUMAN (1-474): 0: 542: 100.00		PHF12_HUMAN (327-381): 1.62e-11: 68.1: 35.09
+	Hs
		782595 HNF4A_HUMAN (1-474): 0: 542: 100.00		KMT2C_HUMAN (274-373): 1.73e-10: 65.1: 20.00
+	Hs
		369621 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		CHD4_HUMAN (63-386): 1.11e-44: 167: 13.48
+	Hs
		370137 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		KAT6A_HUMAN (119-385): 1.98e-44: 166: 29.35
+	Hs
		370701 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		KMT2B_HUMAN (126-384): 1.95e-36: 143: 18.75
+	Hs
		370266 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		UHRF1_HUMAN (86-386): 8.53e-35: 137: 16.51
+	Hs
		331692 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		NSD2_HUMAN (91-377): 7.7e-33: 132: 17.35
+	Hs
		369449 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		KMT2A_HUMAN (74-382): 1.99e-32: 131: 15.97
+	Hs
		152573 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		KMT2D_HUMAN (197-380): 3.16e-27: 116: 24.73
+	Hs
		369044 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		KDM5A_HUMAN (307-379): 8.48e-25: 108: 35.62
+	Hs
		370655 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		BAZ2A_HUMAN (303-379): 1.77e-23: 104: 37.18
+	Hs
		370248 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		PHF12_HUMAN (327-381): 1.62e-11: 68.1: 35.09
+	Hs
		370040 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		KMT2C_HUMAN (274-373): 1.73e-10: 65.1: 20.00
+	Hs
		370600 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		PHRF1_HUMAN (328-372): 5.07e-09: 60.5: 53.33