HitPredict

Interactor 1: HNF4A (P41235)
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)
Gene: HNF4A

Interactor 2: PNRC2 (Q9NPJ4)
Proline-rich nuclear receptor coactivator 2
Gene: PNRC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15604093
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 139
+	Hs
		782531 HNF4A_HUMAN (1-474): 0: 542: 100.00		PNRC1_HUMAN (21-138): 3.26e-54: 174: 41.32
+	Hs
		1055260 HNF4G_HUMAN (52-456): 5.67e-137: 402: 73.58		PNRC2_HUMAN (1-139): 7.18e-68: 203: 100.00
+	Hs
		1016553 HNF4G_HUMAN (52-456): 5.67e-137: 402: 73.58		PNRC1_HUMAN (21-138): 3.26e-54: 174: 41.32
+	Hs
		587199 RXRA_HUMAN (5-377): 4.91e-125: 373: 37.01		PNRC2_HUMAN (1-139): 7.18e-68: 203: 100.00
+	Hs
		370500 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		PNRC2_HUMAN (1-139): 7.18e-68: 203: 100.00
+	Hs
		914676 ERR3_HUMAN (16-375): 8.56e-110: 334: 27.39		PNRC2_HUMAN (1-139): 7.18e-68: 203: 100.00
+	Hs
		488025 RARA_HUMAN (9-382): 7.34e-107: 327: 25.06		PNRC2_HUMAN (1-139): 7.18e-68: 203: 100.00
+	Hs
		530813 RARG_HUMAN (5-404): 3.42e-104: 319: 25.18		PNRC2_HUMAN (1-139): 7.18e-68: 203: 100.00
+	Hs
		500363 RARB_HUMAN (10-424): 2.37e-114: 345: 25.23		PNRC1_HUMAN (21-138): 3.26e-54: 174: 41.32
+	Hs
		1269696 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		PNRC2_HUMAN (1-139): 7.18e-68: 203: 100.00
+	Hs
		914644 ERR3_HUMAN (16-375): 8.56e-110: 334: 27.39		PNRC1_HUMAN (21-138): 3.26e-54: 174: 41.32
+	Hs
		487957 RARA_HUMAN (9-382): 7.34e-107: 327: 25.06		PNRC1_HUMAN (21-138): 3.26e-54: 174: 41.32
+	Hs
		530793 RARG_HUMAN (5-404): 3.42e-104: 319: 25.18		PNRC1_HUMAN (21-138): 3.26e-54: 174: 41.32
+	Hs
		1016558 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		PNRC1_HUMAN (21-138): 3.26e-54: 174: 41.32
+	Hs
		510040 ERR1_HUMAN (59-374): 7.31e-38: 144: 28.90		PNRC2_HUMAN (1-139): 7.18e-68: 203: 100.00