HitPredict

Interactor 1: HNF4A (P41235)
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)
Gene: HNF4A

Interactor 2: TF3C3 (Q9Y5Q9)
General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma)
Gene: GTF3C3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 886
+	Hs
		1270037 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		TF3C3_HUMAN (1-886): 1.1e-146: 457: 100.00
+	Hs
		183074 HNF4A_HUMAN (1-474): 0: 542: 100.00		KDM6A_HUMAN (26-547): 1.3e-11: 70.7: 15.40
+	Hs
		369840 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		SKI3_HUMAN (37-841): 9.67e-24: 110: 10.77
+	Hs
		488016 RARA_HUMAN (9-382): 7.34e-107: 327: 25.06		BBS4_HUMAN (89-481): 9.06e-26: 114: 15.48
+	Hs
		174531 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		OGT1_HUMAN (698-886): 2.34e-17: 89.3: 12.96
+	Hs
		530809 RARG_HUMAN (5-404): 3.42e-104: 319: 25.18		BBS4_HUMAN (89-481): 9.06e-26: 114: 15.48
+	Hs
		370376 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		CRNL1_HUMAN (306-760): 3.03e-16: 85.8: 8.77
+	Hs
		369839 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		CTR9_HUMAN (25-542): 4.17e-16: 85.4: 12.81
+	Hs
		1190470 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		TT21B_HUMAN (131-827): 8.45e-25: 113: 10.12
+	Hs
		1161403 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		SKI3_HUMAN (37-841): 9.67e-24: 110: 10.77
+	Hs
		300025 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		PRP6_HUMAN (6-259): 5.65e-10: 65.4: 10.21
+	Hs
		175077 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		OGT1_HUMAN (698-886): 2.34e-17: 89.3: 12.96
+	Mm
		1142687 ERR2_MOUSE (9-375): 1.5e-99: 307: 27.37		OGT1_MOUSE (698-886): 2.13e-17: 89.7: 12.96
+	Hs
		1160955 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		CTR9_HUMAN (25-542): 4.17e-16: 85.4: 12.81
+	Mm
		1142644 ERR2_MOUSE (9-375): 1.5e-99: 307: 27.37		CTR9_MOUSE (25-542): 1.97e-15: 83.1: 12.81
+	Hs
		611456 NR4A1_HUMAN (11-380): 1.23e-98: 310: 25.00		TMTC4_HUMAN (388-656): 2.55e-12: 72.6: 11.52
+	Hs
		183143 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		KDM6A_HUMAN (26-547): 1.3e-11: 70.7: 15.40