HitPredict

Interactor 1: CSK (P41240)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)
Gene: CSK

Interactor 2: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	7512694
Identification Methods	enzymatic study, affinity chromatography technology, biochemical
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0050852 - T cell receptor signaling pathway GO:1990782 - protein tyrosine kinase binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 443
+	Mm
		763394 FYN_MOUSE (12-442): 1.69e-170: 491: 36.77		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Mm
		980964 YES_MOUSE (12-442): 6.97e-170: 489: 37.08		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Mm
		403437 SRC_MOUSE (12-442): 1.93e-169: 488: 39.55		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		412149 FYN_HUMAN (12-442): 1.26e-170: 491: 36.77		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		522933 SRC_HUMAN (12-442): 8.48e-171: 491: 39.33		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		433330 YES_HUMAN (12-442): 5.99e-170: 490: 37.30		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		411689 LCK_HUMAN (5-443): 1.95e-168: 485: 38.55		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		789110 FRK_HUMAN (5-442): 1.83e-167: 482: 36.17		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		442815 HCK_HUMAN (3-445): 6.38e-167: 481: 36.32		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		454827 FGR_HUMAN (12-442): 4.47e-165: 476: 38.43		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		639447 LYN_MOUSE (4-445): 3.96e-160: 463: 36.90		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		433719 LYN_HUMAN (4-445): 3.75e-160: 463: 37.12		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991758 PTK6_HUMAN (11-447): 3.62e-149: 433: 35.41		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		763412 FYN_MOUSE (12-442): 1.69e-170: 491: 36.77		KHDR2_MOUSE (100-443): 8.36e-126: 370: 61.65
+	Hs
		433822 LYN_HUMAN (4-445): 3.75e-160: 463: 37.12		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Hs
		1046410 PTK6_HUMAN (11-447): 3.62e-149: 433: 35.41		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Dm
		337713 SRC64_DROME (13-443): 2.3e-150: 440: 35.49		Q9W255_DROME (59-398): 6.04e-96: 295: 32.35
+	Hs
		337484 ABL1_HUMAN (5-447): 1.78e-164: 494: 37.83		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		789069 ABL2_HUMAN (4-443): 1.63e-160: 485: 39.33		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33