HitPredict

Interactor 1: CSK (P41240)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)
Gene: CSK

Interactor 2: SRCN1 (Q9C0H9)
SRC kinase signaling inhibitor 1 (SNAP-25-interacting protein) (SNIP) (p130Cas-associated protein) (p140Cap)
Gene: SRCIN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	23383002, 17525734
Identification Methods	far western blotting, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 1183
+	Mm
		763409 FYN_MOUSE (12-442): 1.69e-170: 491: 36.77		SRCN1_MOUSE (2-1183): 0: 1537: 89.32
+	Mm
		403464 SRC_MOUSE (12-442): 1.93e-169: 488: 39.55		SRCN1_MOUSE (2-1183): 0: 1537: 89.32
+	Hs
		337555 ABL1_HUMAN (5-447): 1.78e-164: 494: 37.83		SRCN1_HUMAN (1-1183): 0: 1528: 100.00
+	Hs
		523139 SRC_HUMAN (12-442): 8.48e-171: 491: 39.33		SRCN1_HUMAN (1-1183): 0: 1528: 100.00
+	Mm
		639461 LYN_MOUSE (4-445): 3.96e-160: 463: 36.90		SRCN1_MOUSE (2-1183): 0: 1537: 89.32
+	Hs
		411754 LCK_HUMAN (5-443): 1.95e-168: 485: 38.55		SKT_HUMAN (4-1091): 0: 1138: 37.96
+	Hs
		433813 LYN_HUMAN (4-445): 3.75e-160: 463: 37.12		SKT_HUMAN (4-1091): 0: 1138: 37.96
+	Hs
		1046409 PTK6_HUMAN (11-447): 3.62e-149: 433: 35.41		SKT_HUMAN (4-1091): 0: 1138: 37.96