HitPredict

Interactor 1: EIFCL (B5ME19)
Eukaryotic translation initiation factor 3 subunit C-like protein
Gene: EIF3CL

Interactor 2: EIF3E (P60228)
Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (Viral integration site protein INT-6 homolog) (eIF-3 p48)
Gene: EIF3E

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 28514442, 33961781, 37071682
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains eIF-3c_N~eIF3_N, PCI~eIF-3c_N, PCI~eIF3_N, PCI~PCI
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005852 - eukaryotic translation initiation factor 3 complex
GO:0006413 - translational initiation
and 2 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 914
Hs

1 445
+ Hs
+ Dm
+ At
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024