Interactor 1: SYIC (P41252)
Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)
Gene: IARS1
Interactor 2: SYMC (P56192)
Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)
Gene: MARS1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Anticodon_1~tRNA-synt_1g, Anticodon_3~tRNA-synt_1, tRNA-synt_1~tRNA-synt_1g |
| Common GO terms | GO:0000049 - tRNA binding GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006418 - tRNA aminoacylation for protein translation and 3 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
