HitPredict

Interactor 1: TNFL9 (P41273)
Tumor necrosis factor ligand superfamily member 9 (4-1BB ligand) (4-1BBL)
Gene: TNFSF9

Interactor 2: TNR9 (Q07011)
Tumor necrosis factor receptor superfamily member 9 (4-1BB ligand receptor) (CDw137) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD antigen CD137)
Gene: TNFRSF9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	26186194, 28514442, 33961781, 8088337
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TNF~TNFR_c6
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 254 Hs			1 255
+	Hs
		121451 TNFL9_HUMAN (1-254): 1.49e-148: 416: 100.00		TR10A_HUMAN (31-119): 4.81e-21: 93.3: 24.47
+	Hs
		155888 TNFL9_HUMAN (1-254): 1.49e-148: 416: 100.00		TR10C_HUMAN (30-118): 3.23e-14: 72.1: 21.74
+	Hs
		645790 TNFL9_HUMAN (1-254): 1.49e-148: 416: 100.00		CD27_HUMAN (24-103): 1.03e-12: 67.9: 31.03
+	Mm
		591447 TNFL9_MOUSE (91-245): 7.35e-75: 231: 39.02		TNR9_MOUSE (1-247): 9.28e-58: 186: 56.05