HitPredict

Interactor 1: EIFCL (B5ME19)
Eukaryotic translation initiation factor 3 subunit C-like protein
Gene: EIF3CL

Interactor 2: EIF3L (Q9Y262)
Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein)
Gene: EIF3L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 28514442, 33961781, 37071682
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~Paf67
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005852 - eukaryotic translation initiation factor 3 complex
GO:0006413 - translational initiation
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 914
Hs

1 564
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024