Interactor 1: PTN11 (P41499)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2)
Gene: Ptpn11
Interactor 2: NTRK2 (Q63604)
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B)
Gene: NTRK2
Species: Rattus norvegicus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21946312 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_8~SH2, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~Y_phosphatase |
| Common GO terms | GO:0005829 - cytosol GO:0030971 - receptor tyrosine kinase binding GO:0043408 - regulation of MAPK cascade |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
