Interactor 1: PTN11 (P41499)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2)
Gene: Ptpn11

Interactor 2: T2CB11 (T2CB11)
Tyrosine-protein kinase receptor (EC 2.7.10.1)
Gene: Insr

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 9415395, 9832615
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~fn3, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~Y_phosphatase
Common GO terms GO:0042593 - glucose homeostasis
GO:0043560 - insulin receptor substrate binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 593
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024