HitPredict

Interactor 1: VIPR2 (P41587)
Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Helodermin-preferring VIP receptor) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (PACAP-R3) (VPAC2)
Gene: VIPR2

Interactor 2: CERS5 (Q8N5B7)
Ceramide synthase 5 (CerS5) (LAG1 longevity assurance homolog 5) (Sphingoid base N-palmitoyltransferase CERS5) (EC 2.3.1.291) (Sphingosine N-acyltransferase CERS5) (EC 2.3.1.24)
Gene: CERS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 438 Hs			1 392
+	Hs
		783712 VIPR2_HUMAN (1-438): 3.34e-131: 387: 100.00		CERS2_HUMAN (9-351): 3.27e-128: 375: 44.90
+	Hs
		783662 VIPR2_HUMAN (1-438): 3.34e-131: 387: 100.00		CERS6_HUMAN (9-349): 3.51e-126: 370: 66.28
+	Hs
		686356 VIPR1_HUMAN (12-438): 6.04e-120: 359: 46.05		CERS2_HUMAN (9-351): 3.27e-128: 375: 44.90
+	Hs
		976346 PTH1R_HUMAN (12-422): 3.42e-115: 351: 35.07		CERS6_HUMAN (9-349): 3.51e-126: 370: 66.28
+	Hs
		814278 GLR_HUMAN (20-435): 8.94e-92: 287: 33.94		CERS5_HUMAN (1-392): 7.73e-150: 431: 100.00
+	Hs
		825065 PTH2R_HUMAN (4-438): 5.63e-105: 323: 31.68		CERS6_HUMAN (9-349): 3.51e-126: 370: 66.28
+	Hs
		823055 AGRE5_HUMAN (64-424): 5.84e-80: 265: 18.28		CERS6_HUMAN (9-349): 3.51e-126: 370: 66.28
+	Hs
		1168236 AGRG2_HUMAN (66-419): 2.03e-76: 258: 16.10		CERS6_HUMAN (9-349): 3.51e-126: 370: 66.28