Interactor 1: GRM5 (P41594)
Metabotropic glutamate receptor 5 (mGluR5)
Gene: GRM5

Interactor 2: GRM5 (P41594)
Metabotropic glutamate receptor 5 (mGluR5)
Gene: GRM5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.666

The method score is based on:

Property Details
Experiments 30675062
Identification Methods 3D electron microscopy, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_3~7tm_3, 7tm_3~NCD3G, ANF_receptor~ANF_receptor, ANF_receptor~NCD3G, NCD3G~NCD3G
Common GO terms GO:0001640 - adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO:0002029 - desensitization of G protein-coupled receptor signaling pathway
GO:0004930 - G protein-coupled receptor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 28 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1212
Hs

1 1212
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Last updated: 15 Jul 2024