HitPredict

Interactor 1: CCR2 (P41597)
C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD antigen CD192)
Gene: CCR2

Interactor 2: CCL13 (Q99616)
C-C motif chemokine 13 (CK-beta-10) (Monocyte chemoattractant protein 4) (Monocyte chemotactic protein 4) (MCP-4) (NCC-1) (Small-inducible cytokine A13) [Cleaved into: C-C motif chemokine 13, long chain; C-C motif chemokine 13, medium chain; C-C motif chemokine 13, short chain]
Gene: CCL13

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9195948
Identification Methods	biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0002548 - monocyte chemotaxis GO:0006874 - intracellular calcium ion homeostasis GO:0006935 - chemotaxis GO:0006954 - inflammatory response GO:0070098 - chemokine-mediated signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 374 Hs			1 98
+	Hs
		849619 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL13_HUMAN (1-98): 4.86e-39: 126: 100.00
+	Hs
		561732 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CL3L1_HUMAN (1-93): 1.3e-36: 120: 41.94
+	Hs
		526564 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL4_HUMAN (1-92): 6.96e-36: 118: 39.13
+	Hs
		783815 CCR2_HUMAN (1-374): 5.63e-99: 299: 100.00		CCL8_HUMAN (1-97): 3.41e-32: 109: 62.25
+	Hs
		849616 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL14_HUMAN (1-92): 5.26e-34: 114: 35.48
+	Hs
		486237 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL3_HUMAN (1-93): 1.45e-33: 113: 38.71
+	Hs
		528206 CCR2_HUMAN (1-374): 5.63e-99: 299: 100.00		CCL2_HUMAN (1-98): 6.78e-31: 106: 64.65
+	Hs
		783816 CCR2_HUMAN (1-374): 5.63e-99: 299: 100.00		CCL7_HUMAN (17-97): 1.05e-30: 105: 60.98
+	Hs
		528210 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL2_HUMAN (1-98): 6.78e-31: 106: 64.65
+	Hs
		849614 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL7_HUMAN (17-97): 1.05e-30: 105: 60.98
+	Hs
		849504 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL11_HUMAN (1-97): 2.03e-28: 100: 64.29
+	Hs
		849617 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL15_HUMAN (1-90): 6.93e-28: 99.3: 31.19
+	Hs
		528252 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL5_HUMAN (1-91): 4.66e-27: 96.6: 31.87
+	Hs
		849613 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL18_HUMAN (1-93): 3.43e-27: 96.6: 34.41
+	Hs
		118813 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL24_HUMAN (1-95): 7.7e-26: 94.3: 36.46
+	Hs
		180160 CCR2_HUMAN (1-374): 5.63e-99: 299: 100.00		CCL16_HUMAN (1-88): 8.65e-22: 83.9: 34.07
+	Hs
		849620 CCR3_HUMAN (21-320): 2.71e-96: 292: 53.77		CCL26_HUMAN (23-94): 2.02e-23: 87.3: 37.50
+	Hs
		607528 CCR8_HUMAN (10-325): 3.08e-89: 274: 40.00		CCL1_HUMAN (1-97): 7.09e-28: 98.9: 31.96
+	Hs
		849723 CCR8_HUMAN (10-325): 3.08e-89: 274: 40.00		CCL18_HUMAN (1-93): 3.43e-27: 96.6: 34.41
+	Hs
		180162 CCR8_HUMAN (10-325): 3.08e-89: 274: 40.00		CCL16_HUMAN (1-88): 8.65e-22: 83.9: 34.07