Interactor 1: KPCI (P41743)
Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota)
Gene: PRKCI

Interactor 2: MP2K5 (Q13163)
Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)
Gene: MAP2K5

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 12813044, 11158308
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Pkinase, PB1~PB1, PB1~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0046872 - metal ion binding
GO:0106310 - protein serine kinase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 596
Hs

1 448
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Last updated: 15 Jul 2024