HitPredict

Interactor 1: KPCI (P41743)
Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota)
Gene: PRKCI

Interactor 2: L2GL1 (Q15334)
Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein)
Gene: LLGL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.744

Property	Details
Experiments	26496610, 31980649, 35271311, 14676191, 12725730, unassigned2173, 24366813
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005886 - plasma membrane GO:0045197 - establishment or maintenance of epithelial cell apical/basal polarity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 596 Hs			1 1064
+	Mm
		1143282 KPCI_MOUSE (1-596): 0: 700: 98.32		L2GL1_MOUSE (1-1039): 0: 1350: 90.57
+	Hs
		983844 KPCZ_HUMAN (15-596): 0: 631: 70.34		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Mm
		973812 KPCZ_MOUSE (1-596): 0: 625: 69.04		L2GL1_MOUSE (1-1039): 0: 1350: 90.57
+	Mm
		1111901 KPCI_MOUSE (1-596): 0: 700: 98.32		L2GL2_MOUSE (5-1011): 0: 1228: 55.74
+	Hs
		784030 KPCI_HUMAN (1-596): 0: 706: 100.00		L2GL2_HUMAN (5-979): 0: 1216: 56.97
+	Hs
		983860 KPCZ_HUMAN (15-596): 0: 631: 70.34		L2GL2_HUMAN (5-979): 0: 1216: 56.97
+	Rn
		1144332 AKT3_RAT (120-586): 6.07e-151: 444: 33.19		L2GL1_RAT (1-1039): 0: 1341: 90.38
+	Dm
		54639 APKC_DROME (1-596): 0: 637: 65.67		L2GL_DROME (1-1041): 0: 984: 35.51
+	Ce
		106868 KPC3_CAEEL (15-596): 0: 591: 55.95		G5EEI1_CAEEL (4-941): 0: 810: 20.57