HitPredict

Interactor 1: KPCI (P41743)
Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota)
Gene: PRKCI

Interactor 2: GP156 (Q8NFN8)
Probable G-protein coupled receptor 156 (G-protein coupled receptor PGR28) (GABAB-related G-protein coupled receptor)
Gene: GPR156

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 596 Hs			1 814
+	Rn
		448413 KPCE_RAT (43-590): 2.47e-175: 516: 35.57		CASR_RAT (1-350): 1.09e-87: 302: 14.68
+	Hs
		277380 AKT1_HUMAN (181-586): 1.34e-151: 446: 37.86		GABR2_HUMAN (32-544): 4.64e-114: 370: 24.62
+	Mm
		593483 KPCA_MOUSE (126-190): 7.79e-12: 70.1: 43.08		GRM5_MOUSE (2-731): 8.51e-145: 458: 15.54
+	Hs
		566315 KPCA_HUMAN (111-223): 4.34e-17: 86.9: 24.37		GRM5_HUMAN (2-624): 1.25e-135: 434: 14.77
+	Rn
		404389 KPCA_RAT (111-223): 4.19e-17: 86.9: 25.21		GRM7_RAT (2-357): 9.61e-110: 358: 13.87
+	Hs
		566392 KPCA_HUMAN (111-223): 4.34e-17: 86.9: 24.37		GRM7_HUMAN (2-357): 1.17e-109: 358: 13.87
+	Hs
		408571 KPCB_HUMAN (111-229): 6.31e-18: 89.6: 21.28		CASR_HUMAN (1-350): 8.41e-87: 299: 14.96
+	Hs
		566313 KPCA_HUMAN (111-223): 4.34e-17: 86.9: 24.37		CASR_HUMAN (1-350): 8.41e-87: 299: 14.96
+	Hs
		397145 KPCG_HUMAN (107-190): 1.32e-12: 72.8: 39.29		CASR_HUMAN (1-350): 8.41e-87: 299: 14.96