Interactor 1: KPCI (P41743)
Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota)
Gene: PRKCI

Interactor 2: PAR6B (Q9BYG5)
Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B)
Gene: PARD6B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 26186194, 26496610, 28514442, 32296183, 33961781, 14676191, 23718855, 25416956, 31980649, 35271311, 23439680, 11260256, unassigned1304, unassigned2173
Identification Methods affinity chromatography technology, two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~PB1, PB1~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0016324 - apical plasma membrane
and 4 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 596
Hs

1 372
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Ce
+ Hs

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Last updated: 15 Jul 2024