Interactor 1: KPCI (P41743)
Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota)
Gene: PRKCI

Interactor 2: PAR6A (Q9NPB6)
Partitioning defective 6 homolog alpha (PAR-6) (PAR-6 alpha) (PAR-6A) (PAR6C) (Tax interaction protein 40) (TIP-40)
Gene: PARD6A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 21516116, 26496610, 32296183, 14676191, 11257119, 12813044, 25416956, 16189514, 16861740, 11260256, 15590654, unassigned1304, 17057644
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid prey pooling approach, x-ray crystallography, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, coimmunoprecipitation, anti bait coimmunoprecipitation and 1 others

more...

Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~PB1, PB1~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0016324 - apical plasma membrane
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 596
Hs

1 346
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ Dm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024