HitPredict

Interactor 1: PBX1 (P41778)
Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1)
Gene: PBX1

Interactor 2: MEIS1 (Q60954)
Homeobox protein Meis1 (Myeloid ecotropic viral integration site 1)
Gene: MEIS1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.829

The method score is based on:

Property Details
Experiments 9315626, 20211142, 10373562
Identification Methods affinity chromatography technology, two hybrid array, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Homeobox_KN~Homeobox_KN
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001654 - eye development
GO:0003677 - DNA binding
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 430
Mm

1 390
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024