HitPredict

Interactor 1: COPB2 (P41811)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)
Gene: SEC27

Interactor 2: SEH1 (P53011)
Nucleoporin SEH1 (Nuclear pore protein SEH1) (SEC13 homolog 1)
Gene: SEH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.80	0.679

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 889 Sc			1 349
+	Hs
		725410 COPB2_HUMAN (1-882): 0: 608: 42.26		WDR5_HUMAN (149-345): 9.8e-50: 171: 17.26
+	Hs
		282837 COPB2_HUMAN (1-882): 0: 608: 42.26		CIAO1_HUMAN (7-145): 9.97e-18: 85: 19.87
+	Hs
		903431 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		SEH1_HUMAN (2-347): 1.28e-76: 241: 32.87
+	Hs
		878165 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		SEC13_HUMAN (1-349): 5.74e-69: 220: 24.45
+	Dm
		1358845 WDS_DROME (382-686): 1.68e-51: 186: 8.83		WDS_DROME (103-349): 3.1e-57: 191: 15.73
+	Dm
		1358859 WDS_DROME (382-686): 1.68e-51: 186: 8.83		FBXW7_DROME (2-285): 1.6e-52: 188: 13.54
+	Hs
		903418 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		FBXW7_HUMAN (3-285): 2.49e-55: 193: 13.24
+	Hs
		903349 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		WDR5B_HUMAN (64-349): 3.97e-58: 192: 13.94
+	Hs
		1240442 POC1B_HUMAN (2-168): 1.34e-45: 172: 19.76		POC1A_HUMAN (93-340): 2.07e-54: 185: 13.31
+	Hs
		903077 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		WDR5_HUMAN (149-345): 9.8e-50: 171: 17.26
+	Hs
		863508 COPA_HUMAN (2-418): 5.05e-37: 152: 13.73		FBXW7_HUMAN (3-285): 2.49e-55: 193: 13.24
+	Hs
		903551 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		NLE1_HUMAN (2-243): 8.53e-46: 164: 15.60
+	Hs
		903174 TBL3_HUMAN (3-168): 2.12e-41: 165: 19.28		WDR5_HUMAN (149-345): 9.8e-50: 171: 17.26
+	Hs
		863397 COPA_HUMAN (2-418): 5.05e-37: 152: 13.73		WDR5_HUMAN (149-345): 9.8e-50: 171: 17.26
+	Hs
		792949 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		LIS1_HUMAN (201-349): 1.24e-33: 130: 13.42
+	Hs
		903428 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		SNR40_HUMAN (1-136): 2.54e-24: 103: 17.86
+	Hs
		1016312 TBL3_HUMAN (3-168): 2.12e-41: 165: 19.28		SNR40_HUMAN (1-136): 2.54e-24: 103: 17.86
+	Hs
		282871 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		CIAO1_HUMAN (7-145): 9.97e-18: 85: 19.87
+	Mm
		925836 LIS1_MOUSE (307-571): 5.05e-19: 92.4: 9.03		LIS1_MOUSE (201-349): 9.84e-34: 130: 13.42
+	Hs
		282843 LIS1_HUMAN (307-571): 5.64e-19: 92.4: 9.03		CIAO1_HUMAN (7-145): 9.97e-18: 85: 19.87