Interactor 1: COPB2 (P41811)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)
Gene: SEC27

Interactor 2: COPA (P53622)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (Retrieval from endoplasmic reticulum protein 1) (Secretory protein 22) (Suppressor of osmo-sensitivity 1)
Gene: COP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 11805837, 11805826, 16554755, 37968396, 35904239, 22538654, 22940862, 21435344, 16429126, 10921873, 14699056, 23481256
Identification Methods anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, two hybrid, molecular sieving, isothermal titration calorimetry
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Coatomer_WDAD~Coatomer_WDAD, COPI_C~Coatomer_WDAD, WD40~WD40
Common GO terms GO:0000139 - Golgi membrane
GO:0005198 - structural molecule activity
GO:0006886 - intracellular protein transport
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
and 4 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 889
Sc

1 1201
+ Hs
+ Ce
+ Sc
+ Hs
+ Hs
+ Bt
+ Hs
+ Dm
+ Zm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024