HitPredict

Interactor 1: COPB2 (P41811)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)
Gene: SEC27

Interactor 2: GCN5 (Q03330)
Histone acetyltransferase GCN5 (EC 2.3.1.48) (Histone crotonyltransferase GCN5) (EC 2.3.1.-)
Gene: GCN5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	21734642
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Acetyltransf_1~WD40
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 889 Sc			1 439
+	Sc
		863629 COPA_YEAST (3-887): 8.6e-161: 503: 20.34		GCN5_YEAST (1-439): 0: 543: 100.00
+	Hs
		725424 COPB2_HUMAN (1-882): 0: 608: 42.26		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		244027 COPB2_HUMAN (1-882): 0: 608: 42.26		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		903409 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		KAT2B_HUMAN (2-430): 0: 527: 39.22
+	Hs
		903408 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		KAT2A_HUMAN (14-430): 5.17e-171: 502: 38.30
+	Mm
		903679 WDR5_MOUSE (342-624): 6.55e-49: 178: 11.11		KAT2A_MOUSE (14-430): 1.8e-168: 495: 37.97
+	Dm
		1358857 WDS_DROME (382-686): 1.68e-51: 186: 8.83		Q9VTZ1_DROME (42-432): 3.07e-148: 443: 38.56
+	Hs
		267784 TAF5L_HUMAN (85-266): 1.23e-11: 70.5: 26.37		KAT2B_HUMAN (2-430): 0: 527: 39.22
+	Hs
		267783 TAF5L_HUMAN (85-266): 1.23e-11: 70.5: 26.37		KAT2A_HUMAN (14-430): 5.17e-171: 502: 38.30
+	Hs
		903172 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		244210 WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		863605 COPA_HUMAN (2-418): 5.05e-37: 152: 13.73		TRI33_HUMAN (225-439): 1.05e-41: 160: 20.65
+	Hs
		1016281 TBL3_HUMAN (3-168): 2.12e-41: 165: 19.28		BRD3_HUMAN (303-435): 2.85e-36: 143: 30.44
+	Hs
		244350 TBL3_HUMAN (3-168): 2.12e-41: 165: 19.28		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		863413 COPA_HUMAN (2-418): 5.05e-37: 152: 13.73		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		244163 COPA_HUMAN (2-418): 5.05e-37: 152: 13.73		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		1346965 NLE1_HUMAN (547-664): 5.4e-12: 71.1: 9.24		BAZ2A_HUMAN (234-437): 2.83e-41: 159: 21.40
+	Hs
		1346964 NLE1_HUMAN (547-664): 5.4e-12: 71.1: 9.24		BAZ2B_HUMAN (228-435): 1.92e-39: 153: 25.84