Interactor 1: TRM6 (P41814)
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (General control non-derepressible protein 10) (Protein GCD10) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6)
Gene: GCD10

Interactor 2: TRM61 (P46959)
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 (EC 2.1.1.220) (General control non-derepressible protein 14) (Protein GCD14) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61)
Gene: GCD14

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 9660829, 16554755, 37968396, 10330157, 10779558, 27582183, 17932071, 18719252, 20826334, 22102254, 16429126, 9851972
Identification Methods two hybrid, affinity chromatography technology, biochemical, x-ray crystallography, pull down, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GCD14~Gcd10p
Common GO terms GO:0005634 - nucleus
GO:0030488 - tRNA methylation
GO:0031515 - tRNA (m1A) methyltransferase complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 478
Sc

1 383
+ Hs
+ Dm

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Last updated: 15 Jul 2024