HitPredict

Interactor 1: SSP1A (P41848)
FACT complex subunit SSRP1-A (Facilitates chromatin transcription complex subunit ssrp1-A) (HMG box-containing protein 4) (Structure-specific recognition protein 1-A)
Gene: hmg-4

Interactor 2: H4 (P62784)
Histone H4
Gene: his-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30078731, 35297663
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Rtt106
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006334 - nucleosome assembly
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 697 Ce			1 103
+	Hs
		917167 SSRP1_HUMAN (3-697): 0: 707: 38.50		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Ce
		136663 SSP1B_CAEEL (1-686): 0: 693: 75.40		H4_CAEEL (1-103): 7.75e-49: 152: 100.00
+	Sc
		356709 POB3_YEAST (3-508): 0: 536: 25.76		H4_YEAST (18-103): 1.48e-40: 131: 89.54
+	Hs
		917780 CIC_HUMAN (471-694): 1.7e-31: 134: 14.54		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Hs
		917971 HM20A_HUMAN (456-659): 6.7e-29: 120: 19.90		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Mm
		818683 SOX2_MOUSE (527-695): 2.83e-28: 117: 13.41		H4_MOUSE (1-103): 3.12e-48: 150: 99.03
+	Hs
		918056 HM20B_HUMAN (521-625): 2.24e-15: 79.8: 26.55		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Sc
		356198 NHP6A_YEAST (540-623): 1.69e-21: 91.4: 38.37		H4_YEAST (18-103): 1.48e-40: 131: 89.54
+	Sc
		356199 NHP6B_YEAST (531-625): 2.46e-21: 91: 29.90		H4_YEAST (18-103): 1.48e-40: 131: 89.54
+	Hs
		449647 HMGB1_HUMAN (550-643): 3.32e-12: 68.2: 29.59		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Hs
		175766 HMGB3_HUMAN (558-641): 2.84e-11: 65.2: 32.96		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Hs
		643301 HMGB2_HUMAN (550-643): 5.56e-11: 64.4: 31.63		H4_HUMAN (1-103): 3.12e-48: 150: 99.03